Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2935TonB-dependent receptor; Identified by match to protein family HMM PF00593. (801 aa)    
Predicted Functional Partners:
AFE_0770
Identified by match to protein family HMM TIGR01352.
  
   0.838
AFE_3002
TonB family protein.
  
   0.783
AFE_3230
Hypothetical protein; Identified by glimmer; putative.
  
    0.783
AFE_2268
Identified by match to protein family HMM TIGR01352.
  
   0.779
AFE_2998
TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.774
AFE_2274
Conserved hypothetical protein; Identified by similarity to PIR:AG1979; match to protein family HMM PF01436; match to protein family HMM PF08450.
  
    0.770
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
  
     0.765
cyc2
Cytochrome c; Identified by similarity to GB:CAA07031.1.
  
     0.765
AFE_0969
Type IV pilin, putative; Identified by match to protein family HMM TIGR02532.
  
     0.758
AFE_1428
Cytochrome c; Identified by similarity to GB:CAA07031.1.
  
     0.758
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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