Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_2947Thiol:disulfide interchange protein DsbG, putative; Identified by similarity to SP:P77202. (302 aa)    
Predicted Functional Partners:
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
  
     0.658
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.639
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.592
AFE_1497
Conserved hypothetical protein; Identified by match to protein family HMM PF03573.
  
    0.574
AFE_1855
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.572
AFE_1991
Conserved hypothetical protein; Identified by similarity to GB:BAC50343.1; match to protein family HMM PF03573.
  
    0.558
AFE_2292
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.539
rsfS
Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.537
rlmH
Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.537
AFE_2040
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.533
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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