Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_2959Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. (93 aa)    
Predicted Functional Partners:
sspB
Identified by similarity to SP:P25663; match to protein family HMM PF04386.
  
     0.666
ygfZ
Folate-binding protein YgfZ; Identified by match to protein family HMM PF01571; match to protein family HMM TIGR03317; Belongs to the GcvT family.
  
  
 0.493
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
     0.477
AFE_0850
Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.470
bamE
Lipoprotein, SmpA/OmlA family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
    0.467
holA
DNA polymerase III, delta subunit; Identified by similarity to SP:P28630; match to protein family HMM PF06144; match to protein family HMM TIGR01128.
  
     0.458
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.
  
     0.434
apaH
Bis(5-nucleosyl)-tetraphosphatase (symmetrical); Identified by match to protein family HMM PF00149.
  
     0.421
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
     0.400
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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