Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_2967Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534. (1915 aa)    
Predicted Functional Partners:
AFE_2965
Hypothetical protein; Identified by glimmer; putative.
       0.705
AFE_2979
WbbD domain protein; Identified by similarity to GB:AAF04382.1; match to protein family HMM PF08241; match to protein family HMM PF08242.
  
     0.665
AFE_2964
Methyltransferase, FkbM family domain protein; Identified by match to protein family HMM TIGR01444.
 
     0.642
ctrD
Capsule polysaccharide exporter, ATP-binding protein; Identified by similarity to SP:P32016; match to protein family HMM PF00005.
 
 
 0.606
AFE_2969
Hypothetical protein; Identified by glimmer; putative.
 
     0.601
AFE_2968
Hypothetical protein; Identified by glimmer; putative.
      
0.542
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
 0.531
ctrC
Capsule polysaccharide exporter, inner-membrane protein CtrC; Identified by similarity to SP:P32015; match to protein family HMM PF01061.
 
    0.529
AFE_2976
Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534.
 
    
0.459
AFE_2960
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
  
 0.455
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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