Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFE_2976Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534. (389 aa)    
Predicted Functional Partners:
AFE_2975
Capsule polysaccharide export protein, BexD/CtrA/VexA family; Identified by similarity to SP:P22236; match to protein family HMM PF02563.
 
    0.912
AFE_3012
Capsule polysaccharide biosynthesis protein; Identified by match to protein family HMM PF05159.
    0.828
ctrD
Capsule polysaccharide exporter, ATP-binding protein; Identified by similarity to SP:P32016; match to protein family HMM PF00005.
 
 
 0.679
AFE_2961
Capsule polysaccharide export inner-membrane protein; Identified by similarity to SP:P32014.
  
    0.671
ctrC
Capsule polysaccharide exporter, inner-membrane protein CtrC; Identified by similarity to SP:P32015; match to protein family HMM PF01061.
  
    0.630
AFE_2979
WbbD domain protein; Identified by similarity to GB:AAF04382.1; match to protein family HMM PF08241; match to protein family HMM PF08242.
     0.625
AFE_3013
Capsule polysaccharide modification protein; Identified by similarity to SP:Q05014; match to protein family HMM PF05159.
  
     0.606
cysQ
3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
       0.533
AFE_2974
Conserved hypothetical protein; Identified by similarity to GB:AAO77300.1.
       0.533
gmd-1
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
    0.500
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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