Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2985ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. (618 aa)    
Predicted Functional Partners:
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 0.855
AFE_1502
Ankyrin repeat protein/rhodanese-like domain protein; Identified by match to protein family HMM PF00023; match to protein family HMM PF00581.
   
 0.813
AFE_2987
Peptide ABC transporter, periplasmic peptide-binding protein; Identified by similarity to SP:P42061; match to protein family HMM PF00496.
 
   
 0.611
AFE_2986
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
       0.592
AFE_2534
Identified by match to protein family HMM PF00850.
  
  0.574
AFE_1499
ATPase, AAA family; Identified by match to protein family HMM PF00004.
   
 0.524
AFE_2167
Toxin secretion ABC transporter, ATP-binding protein, HlyB family; Identified by similarity to SP:P22520; match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412.
   
   0.505
AFE_2693
Type I secretion system ATPase; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01846.
   
   0.505
dnaK
Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.469
AFE_3030
Sugar isomerase, KpsF/GutQ family; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily.
     
 0.445
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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