close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2995Conserved domain protein; Identified by similarity to GB:CAD11970.1. (72 aa)    
Predicted Functional Partners:
AFE_2993
Conserved hypothetical protein; Identified by similarity to GB:AAM36869.1.
       0.773
AFE_2994
Conserved hypothetical protein; Identified by similarity to GB:AAM36869.1.
       0.773
AFE_2992
Peptide ABC transporter, periplasmic peptide-binding protein; Identified by similarity to SP:P42061; match to protein family HMM PF00496.
       0.482
AFE_2996
Hypothetical protein; Identified by glimmer; putative.
       0.407
AFE_2991
Peptide ABC transporter, permease protein; Identified by similarity to SP:P50989; match to protein family HMM PF00528.
       0.405
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.