Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_2998TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715. (799 aa)    
Predicted Functional Partners:
AFE_0770
Identified by match to protein family HMM TIGR01352.
  
   0.832
AFE_3002
TonB family protein.
 
   0.831
AFE_2935
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.774
cyc2
Cytochrome c; Identified by similarity to GB:CAA07031.1.
  
     0.765
AFE_1428
Cytochrome c; Identified by similarity to GB:CAA07031.1.
  
     0.758
AFE_0620
Hypothetical protein; Identified by glimmer; putative.
  
     0.752
AFE_2040
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.741
AFE_1755
Conserved hypothetical protein; Identified by similarity to GB:AAN66820.1.
  
     0.731
AFE_0771
Identified by match to protein family HMM PF02133; Belongs to the purine-cytosine permease (2.A.39) family.
  
     0.721
AFE_3230
Hypothetical protein; Identified by glimmer; putative.
  
    0.706
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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