AFE_3000 protein (Acidithiobacillus ferrooxidans)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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co-expression

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[Homology]

Score

AFE_3000

Identified by similarity to SP:Q60176; match to protein family HMM PF00056. (355 aa)

Predicted Functional Partners:

citZ

0.998

fumC

0.987

AFE_0660

0.985

icd

0.966

AFE_0423

0.961

atpA

0.938

aspC

0.932

ppc

0.930

groEL

0.923

AFE_3010

0.921

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_0423	AFE_0660	AFE_0423	AFE_0660	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	0.659
AFE_0423	AFE_3000	AFE_0423	AFE_3000	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	Identified by similarity to SP:Q60176; match to protein family HMM PF00056.	0.961
AFE_0423	AFE_3010	AFE_0423	AFE_3010	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.580
AFE_0423	atpA	AFE_0423	AFE_3205	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	0.921
AFE_0423	citZ	AFE_0423	AFE_3065	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	Citrate synthase II; Identified by similarity to SP:P39120; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	0.997
AFE_0423	fumC	AFE_0423	AFE_2673	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.967
AFE_0423	groEL	AFE_0423	AFE_0542	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.797
AFE_0423	icd	AFE_0423	AFE_0424	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183.	0.993
AFE_0660	AFE_0423	AFE_0660	AFE_0423	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	0.659
AFE_0660	AFE_3000	AFE_0660	AFE_3000	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	Identified by similarity to SP:Q60176; match to protein family HMM PF00056.	0.985
AFE_0660	AFE_3010	AFE_0660	AFE_3010	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.506
AFE_0660	atpA	AFE_0660	AFE_3205	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	0.522
AFE_0660	citZ	AFE_0660	AFE_3065	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	Citrate synthase II; Identified by similarity to SP:P39120; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	0.939
AFE_0660	fumC	AFE_0660	AFE_2673	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.970
AFE_0660	groEL	AFE_0660	AFE_0542	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.532
AFE_0660	icd	AFE_0660	AFE_0424	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183.	0.555
AFE_3000	AFE_0423	AFE_3000	AFE_0423	Identified by similarity to SP:Q60176; match to protein family HMM PF00056.	Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342.	0.961
AFE_3000	AFE_0660	AFE_3000	AFE_0660	Identified by similarity to SP:Q60176; match to protein family HMM PF00056.	Malic enzyme family protein; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF03949.	0.985
AFE_3000	AFE_3010	AFE_3000	AFE_3010	Identified by similarity to SP:Q60176; match to protein family HMM PF00056.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.921
AFE_3000	aspC	AFE_3000	AFE_2022	Identified by similarity to SP:Q60176; match to protein family HMM PF00056.	Aspartate aminotransferase; Identified by similarity to SP:P23034; match to protein family HMM PF00155.	0.932