Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_3013Capsule polysaccharide modification protein; Identified by similarity to SP:Q05014; match to protein family HMM PF05159. (436 aa)    
Predicted Functional Partners:
AFE_3012
Capsule polysaccharide biosynthesis protein; Identified by match to protein family HMM PF05159.
   
 0.980
AFE_3014
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     0.963
AFE_3016
Capsular polysaccharide biosynthesis protein, putative; Identified by similarity to GB:CAA45491.1; match to protein family HMM PF00884.
 
   
 0.957
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
 
     0.892
AFE_2961
Capsule polysaccharide export inner-membrane protein; Identified by similarity to SP:P32014.
 
 
 
 0.840
ctrD
Capsule polysaccharide exporter, ATP-binding protein; Identified by similarity to SP:P32016; match to protein family HMM PF00005.
 
   
 0.824
ctrC
Capsule polysaccharide exporter, inner-membrane protein CtrC; Identified by similarity to SP:P32015; match to protein family HMM PF01061.
 
   
 0.816
AFE_2975
Capsule polysaccharide export protein, BexD/CtrA/VexA family; Identified by similarity to SP:P22236; match to protein family HMM PF02563.
 
   
 0.792
AFE_3011
8-amino-7-oxononanoate synthase, putative; Identified by match to protein family HMM PF00155; match to protein family HMM PF00202.
 
     0.788
AFE_2976
Glycosyl transferase, group 1; Identified by match to protein family HMM PF00534.
  
     0.606
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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