lptA protein (Acidithiobacillus ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_1958	lptA	AFE_1958	AFE_3027	Outer membrane protein, OMP85 family; Identified by match to protein family HMM PF01103; match to protein family HMM PF07244.	Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.	0.555
AFE_1958	lptD	AFE_1958	AFE_3034	Outer membrane protein, OMP85 family; Identified by match to protein family HMM PF01103; match to protein family HMM PF07244.	Organic solvent tolerance protein, putative; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.	0.675
AFE_3021	AFE_3023	AFE_3021	AFE_3023	ATPase; Displays ATPase and GTPase activities.	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	0.925
AFE_3021	AFE_3026	AFE_3021	AFE_3026	ATPase; Displays ATPase and GTPase activities.	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	0.494
AFE_3021	AFE_3028	AFE_3021	AFE_3028	ATPase; Displays ATPase and GTPase activities.	Hypothetical protein; Identified by glimmer; putative.	0.485
AFE_3021	AFE_3030	AFE_3021	AFE_3030	ATPase; Displays ATPase and GTPase activities.	Sugar isomerase, KpsF/GutQ family; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily.	0.472
AFE_3021	kdsC	AFE_3021	AFE_3029	ATPase; Displays ATPase and GTPase activities.	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Identified by similarity to SP:P45396; match to protein family HMM TIGR01662; match to protein family HMM TIGR01670.	0.455
AFE_3021	lptA	AFE_3021	AFE_3027	ATPase; Displays ATPase and GTPase activities.	Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.	0.543
AFE_3021	rpoN	AFE_3021	AFE_3025	ATPase; Displays ATPase and GTPase activities.	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.569
AFE_3021	yfiA	AFE_3021	AFE_3024	ATPase; Displays ATPase and GTPase activities.	Ribosomal subunit interface protein; Identified by similarity to SP:P24694; match to protein family HMM PF02482; match to protein family HMM TIGR00741.	0.836
AFE_3023	AFE_3021	AFE_3023	AFE_3021	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	ATPase; Displays ATPase and GTPase activities.	0.925
AFE_3023	AFE_3026	AFE_3023	AFE_3026	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	0.618
AFE_3023	AFE_3028	AFE_3023	AFE_3028	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	Hypothetical protein; Identified by glimmer; putative.	0.571
AFE_3023	AFE_3030	AFE_3023	AFE_3030	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	Sugar isomerase, KpsF/GutQ family; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily.	0.546
AFE_3023	kdsC	AFE_3023	AFE_3029	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Identified by similarity to SP:P45396; match to protein family HMM TIGR01662; match to protein family HMM TIGR01670.	0.531
AFE_3023	lptA	AFE_3023	AFE_3027	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.	0.620
AFE_3023	rpoN	AFE_3023	AFE_3025	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.775
AFE_3023	yfiA	AFE_3023	AFE_3024	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	Ribosomal subunit interface protein; Identified by similarity to SP:P24694; match to protein family HMM PF02482; match to protein family HMM TIGR00741.	0.962
AFE_3026	AFE_3021	AFE_3026	AFE_3021	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	ATPase; Displays ATPase and GTPase activities.	0.494
AFE_3026	AFE_3023	AFE_3026	AFE_3023	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.	0.618