Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_3028Hypothetical protein; Identified by glimmer; putative. (189 aa)    
Predicted Functional Partners:
AFE_3026
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
  
 0.999
lptA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
  
 
 0.990
AFE_2200
Identified by match to protein family HMM PF03739.
  
 
 0.910
AFE_2199
Identified by match to protein family HMM PF03739.
  
 
 0.909
kdsC
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Identified by similarity to SP:P45396; match to protein family HMM TIGR01662; match to protein family HMM TIGR01670.
  
  
 0.847
AFE_3030
Sugar isomerase, KpsF/GutQ family; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily.
  
  
 0.831
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
    0.819
yfiA
Ribosomal subunit interface protein; Identified by similarity to SP:P24694; match to protein family HMM PF02482; match to protein family HMM TIGR00741.
     
 0.579
AFE_3023
Phosphoenolpyruvate-dependent sugar PTS system, EIIA component; Identified by match to protein family HMM PF00359.
       0.571
lptD
Organic solvent tolerance protein, putative; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
  
 0.551
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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