Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gshBGlutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM PF08443; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. (312 aa)    
Predicted Functional Partners:
gshA
Glutamate--cysteine ligase; Identified by match to protein family HMM PF08886; match to protein family HMM TIGR02049.
    
 0.982
AFE_0367
AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.
 
  
 0.948
gor
Glutathione reductase; Identified by similarity to SP:P06715; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01421.
     
 0.946
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.939
AFE_0177
Identified by similarity to GB:AAQ60970.1; match to protein family HMM PF02798.
  
  
 0.937
gst
Glutathione S-transferase; Identified by similarity to GB:CAB57289.1; match to protein family HMM PF00043; match to protein family HMM PF02798.
  
  
 0.936
AFE_1474
Glutathione S-transferase, putative; Identified by similarity to SP:P39100; match to protein family HMM PF02798.
  
  
 0.926
pepN
Identified by similarity to SP:P04825; match to protein family HMM PF01433; match to protein family HMM TIGR02414.
    
 0.911
AFE_0291
Identified by match to protein family HMM PF02798.
     
 0.904
citZ
Citrate synthase II; Identified by similarity to SP:P39120; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.
     
 0.803
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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