Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_3086Plasma-membrane proton-efflux P-type ATPase, putative; Identified by match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494. (763 aa)    
Predicted Functional Partners:
AFE_0818
Plasma-membrane proton-efflux P-type ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01647.
  
  
 
0.909
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
  0.900
AFE_3087
Hypothetical protein; Identified by glimmer; putative.
       0.773
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
       0.582
AFE_3088
Hypothetical protein; Identified by glimmer; putative.
       0.572
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
       0.528
AFE_3090
Membrane protein, putative; Identified by match to protein family HMM PF07690.
       0.470
AFE_3091
Hypothetical protein; Identified by glimmer; putative.
       0.465
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.440
AFE_1716
GTP-binding protein.
  
  
  0.420
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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