Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_3093Cation channel protein, putative; Identified by similarity to SP:P31069; match to protein family HMM PF00520; match to protein family HMM PF02254; match to protein family HMM PF07885. (420 aa)    
Predicted Functional Partners:
moaE
Molybdopterin converting factor, subunit 2; Identified by similarity to SP:P30749; match to protein family HMM PF02391.
   
    0.678
ysxC
Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
       0.580
AFE_3090
Membrane protein, putative; Identified by match to protein family HMM PF07690.
 
     0.547
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
    0.522
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
    0.514
AFE_2019
Conserved domain protein.
  
     0.487
AFE_1498
ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.
  
     0.477
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
 
     0.473
AFE_3091
Hypothetical protein; Identified by glimmer; putative.
       0.453
AFE_1968
Potassium-efflux system protein; Identified by match to protein family HMM PF00999; match to protein family HMM PF02080; match to protein family HMM PF02254; match to protein family HMM TIGR01409; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.449
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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