Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_3096Conserved hypothetical protein; Identified by similarity to GB:AAQ58453.1. (111 aa)    
Predicted Functional Partners:
AFE_2033
Conserved domain protein; Identified by match to protein family HMM PF03413.
  
    0.911
AFE_1968
Potassium-efflux system protein; Identified by match to protein family HMM PF00999; match to protein family HMM PF02080; match to protein family HMM PF02254; match to protein family HMM TIGR01409; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
   
    0.780
thrB
Homoserine kinase; Identified by match to protein family HMM PF01636; match to protein family HMM TIGR00938; Belongs to the pseudomonas-type ThrB family.
  
    0.778
AFE_3095
Conserved hypothetical protein TIGR00730; Identified by similarity to GB:CAD85380.1; match to protein family HMM PF03641; match to protein family HMM TIGR00730; Belongs to the LOG family.
       0.743
AFE_0475
Conserved hypothetical protein; Identified by similarity to GB:AAQ60147.1.
  
     0.719
AFE_0650
Conserved hypothetical protein; Identified by similarity to PIR:H83630.
  
     0.604
AFE_0168
Hypothetical protein; Identified by glimmer; putative.
  
     0.599
polI
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.588
AFE_2390
Conserved hypothetical protein; Identified by similarity to GB:AAQ61663.1.
  
     0.533
AFE_2811
Lipoprotein, putative.
  
     0.494
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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