Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_3099Hypothetical protein; Identified by glimmer; putative. (200 aa)    
Predicted Functional Partners:
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
  
     0.750
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.746
AFE_0969
Type IV pilin, putative; Identified by match to protein family HMM TIGR02532.
  
     0.713
AFE_2019
Conserved domain protein.
  
     0.713
AFE_2040
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.712
AFE_2352
Conserved hypothetical protein; Identified by similarity to GB:BAC47910.1; match to protein family HMM PF00891; match to protein family HMM PF08241; match to protein family HMM PF08242.
  
     0.701
AFE_0458
Rare lipoprotein B, putative; Identified by similarity to SP:P10101.
  
     0.689
AFE_3115
Conserved hypothetical protein; Identified by similarity to SP:O67860.
  
     0.686
AFE_2935
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.672
doxD_2
Identified by match to protein family HMM PF07681.
  
     0.671
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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