Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cycA-1Cytochrome c4; Identified by match to protein family HMM PF00034. (234 aa)    
Predicted Functional Partners:
petC-1
Ubiquinol--cytochrome c reductase, cytochrome c1 subunit; Identified by match to protein family HMM PF02167.
 
 
 
 0.939
petA-1
Ubiquinol--cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 
 0.937
petC-2
Ubiquinol--cytochrome c reductase, cytochrome c1 subunit; Identified by match to protein family HMM PF02167.
 
 
 
 0.892
petB-1
Ubiquinol--cytochrome c reductase, cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 
 0.859
petA-2
Ubiquinol--cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 
 0.853
sdr_1
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; match to protein family HMM PF08659.
 
     0.819
petB-2
Ubiquinol--cytochrome c reductase, cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 
 0.740
cyc2
Cytochrome c; Identified by similarity to GB:CAA07031.1.
      
 0.724
AFE_1652
Oxidoreductase alpha (molybdopterin) subunit; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01701; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
 
 0.599
AFE_2601
Pyridine nucleotide-disulfide oxidoreductase; Identified by similarity to SP:Q9R112; match to protein family HMM PF07992.
   
 
 0.590
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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