Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
resBCytochrome c-type biogenesis protein ResB; Identified by match to protein family HMM PF05140. (614 aa)    
Predicted Functional Partners:
resC
Cytochrome c-type biogenesis protein ResC; Identified by match to protein family HMM PF01578; match to protein family HMM TIGR03144.
 
  
 0.995
AFE_3120
Membrane protein, putative.
  
     0.774
AFE_1769
Oxidoreductase, FAD-binding, putative; Identified by similarity to GB:AAQ61895.1; match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913.
  
     0.674
AFE_0199
Conserved hypothetical protein; Identified by similarity to GB:CAE34827.1.
  
     0.598
AFE_0444
Conserved hypothetical protein; Identified by similarity to GB:AAQ59662.1.
  
     0.577
AFE_2675
Conserved hypothetical protein; Identified by similarity to GB:CAD84648.1.
  
     0.575
AFE_2494
Conserved hypothetical protein; Identified by similarity to GB:AAQ59662.1.
  
     0.559
cobA
uroporphyrin-III C-methyltransferase; Identified by similarity to SP:P21631; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.
  
    0.474
coxB
Cytochrome c oxidase, aa3-type, subunit II; Identified by similarity to GB:CAA07034.1; match to protein family HMM PF00116.
   
  
 0.469
pstC_2
Phosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
      
 0.447
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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