Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
resCCytochrome c-type biogenesis protein ResC; Identified by match to protein family HMM PF01578; match to protein family HMM TIGR03144. (352 aa)    
Predicted Functional Partners:
resB
Cytochrome c-type biogenesis protein ResB; Identified by match to protein family HMM PF05140.
 
  
 0.995
AFE_3120
Membrane protein, putative.
  
     0.770
AFE_1066
Pilus assembly protein TraF, putative.
  
  
 0.658
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
    0.580
AFE_1769
Oxidoreductase, FAD-binding, putative; Identified by similarity to GB:AAQ61895.1; match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913.
 
    0.552
AFE_0199
Conserved hypothetical protein; Identified by similarity to GB:CAE34827.1.
  
     0.545
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.513
coxB
Cytochrome c oxidase, aa3-type, subunit II; Identified by similarity to GB:CAA07034.1; match to protein family HMM PF00116.
  
  
 0.496
cobA
uroporphyrin-III C-methyltransferase; Identified by similarity to SP:P21631; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.
  
    0.471
AFE_3114
Conserved hypothetical protein; Identified by similarity to PIR:C70335.
       0.455
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.