Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_3115Conserved hypothetical protein; Identified by similarity to SP:O67860. (161 aa)    
Predicted Functional Partners:
AFE_0969
Type IV pilin, putative; Identified by match to protein family HMM TIGR02532.
  
     0.740
AFE_0620
Hypothetical protein; Identified by glimmer; putative.
  
     0.735
AFE_2935
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.722
AFE_1755
Conserved hypothetical protein; Identified by similarity to GB:AAN66820.1.
  
     0.719
AFE_3099
Hypothetical protein; Identified by glimmer; putative.
  
     0.686
AFE_2037
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
  
     0.682
AFE_2040
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.678
AFE_2998
TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.673
AFE_0763
TonB-dependent receptor, putative; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.666
AFE_3229
TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.657
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.