Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_3142Major facilitator family transporter; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690. (397 aa)    
Predicted Functional Partners:
AFE_3144
Membrane protein, putative.
     
 0.911
AFE_3139
Hypothetical protein; Identified by glimmer; putative.
     
 0.853
AFE_3141
Identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738.
       0.746
cyoE-2
Protoheme IX farnesyltransferase; Identified by similarity to SP:P56938; match to protein family HMM PF01040; match to protein family HMM TIGR01473.
       0.729
cyoE-1
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
     
 0.475
AFE_2552
Conserved hypothetical protein; Identified by similarity to PIR:H70335.
      
 0.440
sdr_1
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; match to protein family HMM PF08659.
      
 0.440
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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