htpG protein (Acidithiobacillus ferrooxidans)

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htpG

Heat shock protein HtpG; Molecular chaperone. Has ATPase activity. (629 aa)

Predicted Functional Partners:

dnaJ

0.992

hscA

0.987

dnaK

0.987

groEL

0.982

cbpA

0.979

ppiB

0.953

groES

0.903

AFE_2534

0.896

grpE

0.894

AFE_3010

0.891

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_2534	AFE_3010	AFE_2534	AFE_3010	Identified by match to protein family HMM PF00850.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.893
AFE_2534	cbpA	AFE_2534	AFE_3102	Identified by match to protein family HMM PF00850.	Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556.	0.774
AFE_2534	dnaJ	AFE_2534	AFE_2664	Identified by match to protein family HMM PF00850.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.771
AFE_2534	dnaK	AFE_2534	AFE_2665	Identified by match to protein family HMM PF00850.	Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.684
AFE_2534	groEL	AFE_2534	AFE_0542	Identified by match to protein family HMM PF00850.	Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.756
AFE_2534	hscA	AFE_2534	AFE_0677	Identified by match to protein family HMM PF00850.	Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.684
AFE_2534	htpG	AFE_2534	AFE_3158	Identified by match to protein family HMM PF00850.	Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.	0.896
AFE_2534	ppiB	AFE_2534	AFE_1986	Identified by match to protein family HMM PF00850.	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.831
AFE_3010	AFE_2534	AFE_3010	AFE_2534	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Identified by match to protein family HMM PF00850.	0.893
AFE_3010	cbpA	AFE_3010	AFE_3102	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556.	0.950
AFE_3010	dnaJ	AFE_3010	AFE_2664	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.950
AFE_3010	dnaK	AFE_3010	AFE_2665	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.864
AFE_3010	groEL	AFE_3010	AFE_0542	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.840
AFE_3010	groES	AFE_3010	AFE_0543	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.584
AFE_3010	hscA	AFE_3010	AFE_0677	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.864
AFE_3010	htpG	AFE_3010	AFE_3158	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.	0.891
AFE_3010	ppiB	AFE_3010	AFE_1986	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.978
cbpA	AFE_2534	AFE_3102	AFE_2534	Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556.	Identified by match to protein family HMM PF00850.	0.774
cbpA	AFE_3010	AFE_3102	AFE_3010	Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.950
cbpA	dnaK	AFE_3102	AFE_2665	Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556.	Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.991