Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mrrMrr restriction system protein; Identified by similarity to SP:P24202; match to protein family HMM PF04471. (305 aa)    
Predicted Functional Partners:
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
      
 0.763
galU
UTP-glucose-1-phosphate uridylyltransferase; Identified by similarity to SP:Q05852; match to protein family HMM PF00483; match to protein family HMM TIGR01099.
      
 0.761
sreB
Sulfur reductase, iron-sulfur binding subunit; Identified by similarity to GB:CAC86938.1; match to protein family HMM PF00037.
   
    0.760
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (36%) [HD]