Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_3194ATP-dependent DNA helicase RecG domain protein; Identified by similarity to SP:O50224; match to protein family HMM PF04326. (403 aa)    
Predicted Functional Partners:
AFE_0827
ATP-dependent DNA helicase, putative; Identified by similarity to SP:O50224.
  
  
 
0.929
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
     
  0.900
AFE_3193
PHP domain protein.
 
     0.835
AFE_2380
Conserved domain protein; Identified by similarity to GB:AAO78433.1.
 
     0.732
AFE_3192
Type III restriction-modification system, Mod subunit; Identified by match to protein family HMM PF01555.
 
     0.703
AFE_3191
Type III restriction-modification system, Res subunit; Identified by match to protein family HMM PF04851.
 
     0.678
AFE_0092
Fic family protein; Identified by match to protein family HMM PF02661.
 
     0.458
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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