STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnsB-2Identified by similarity to PIR:T45495; match to protein family HMM PF00665. (721 aa)    
Predicted Functional Partners:
tnsC-2
Tn5468, transposition protein C; Identified by similarity to PIR:T45496.
 
 
 0.965
tnsA-2
Identified by similarity to PIR:T45494; match to protein family HMM PF08721; match to protein family HMM PF08722.
  
 0.955
tnsD-2
Tn5468, transposition protein D; Identified by similarity to PIR:T45497.
 
     0.945
tnsC-1
Tn5468, transposition protein C; Identified by similarity to PIR:T45496.
 
 
 0.854
tnsA-1
Identified by similarity to PIR:T45494; match to protein family HMM PF08721; match to protein family HMM PF08722.
  
 0.811
tnsD-1
Tn5468, transposition protein D; Identified by similarity to PIR:T45497.
 
     0.778
AFE_3195
Tn5468, orf5; Identified by similarity to PIR:T45498.
       0.716
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
       0.481
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
       0.407
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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