Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_3223WrbA family protein; Identified by similarity to SP:P30849; Belongs to the WrbA family. (150 aa)    
Predicted Functional Partners:
wrbA
Trp repressor binding protein; Identified by similarity to SP:P30849; match to protein family HMM PF00258; match to protein family HMM TIGR01755.
  
  
 
0.902
ubiE
Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
     
  0.900
AFE_3224
Pirin family protein; Identified by similarity to SP:O00625; match to protein family HMM PF02678; match to protein family HMM PF05726; Belongs to the pirin family.
       0.784
AFE_0115
Conserved domain protein; Identified by match to protein family HMM PF03724.
   
    0.753
AFE_1802
Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.
   
    0.683
AFE_3225
Hypothetical protein; Identified by glimmer; putative.
       0.618
AFE_1575
Type I restriction-modification system, R subunit; Identified by similarity to SP:P08956; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463.
      
 0.604
AFE_1577
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.
      
 0.604
AFE_1636
Hypothetical protein; Identified by glimmer; putative.
      
 0.604
AFE_1651
Identified by similarity to SP:O34969; match to protein family HMM PF03446; match to protein family HMM PF03807.
   
  
 0.604
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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