Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_3238Ferredoxin, putative; Identified by similarity to SP:P07324. (105 aa)    
Predicted Functional Partners:
nuoE
NADH-quinone oxidoreductase, E subunit; Identified by match to protein family HMM PF01257; match to protein family HMM TIGR01958.
 
 
 0.933
AFE_1512
Ferredoxin; Identified by similarity to SP:P46036; match to protein family HMM PF00037; match to protein family HMM TIGR02936.
  
 
 0.927
AFE_0004
Conserved hypothetical protein; Identified by similarity to GB:AAO90130.1.
   
 
 0.878
nuoM
NADH-quinone oxidoreductase, M subunit; Identified by similarity to SP:P50974; match to protein family HMM PF00361; match to protein family HMM TIGR01972.
  
    0.831
gltD
Glutamate synthase, small subunit; Identified by similarity to SP:P09832; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01318.
   
 
 0.823
nuoG
NADH-quinone oxidoreductase, G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
 
 0.743
AFE_3237
Conserved hypothetical protein; Identified by similarity to GB:AAO91263.1.
 
     0.688
coq7
Coq7 family protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
 
     0.650
AFE_3236
ABC transporter, ATP-binding protein, NodI family; Identified by match to protein family HMM PF00005.
       0.612
AFE_3235
ABC-2 type transporter, permease protein, NodJ family; Identified by match to protein family HMM PF01061; match to protein family HMM TIGR01291.
       0.597
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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