Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gph-2Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (227 aa)    
Predicted Functional Partners:
AFE_2218
HAD-superfamily hydrolase, subfamily IA; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549.
  
  
 
0.920
cbbS-2
Ribulose bisphosphate carboxylase, small subunit; Identified by match to protein family HMM PF00101.
    
 0.905
cbbS-1
Ribulose bisphosphate carboxylase, small subunit; Identified by match to protein family HMM PF00101.
    
 0.905
glcE
Glycolate oxidase, subunit GlcE; Identified by similarity to SP:P52073; match to protein family HMM PF01565.
    
 0.902
glcD
Glycolate oxidase, subunit GlcD; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.
    
 0.902
cbbL-2
Ribulose bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily.
    
  0.902
cbbL2
Ribulose bisphosphate carboxylase, large subunit 2; Identified by match to protein family HMM PF00016; match to protein family HMM PF02493; match to protein family HMM PF02788; Belongs to the RuBisCO large chain family.
    
  0.902
cbbL-1
Ribulose bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily.
    
  0.902
glcF
Glycolate oxidase, iron-sulfur subunit; Identified by similarity to SP:P52074; match to protein family HMM PF00037; match to protein family HMM PF02754.
     
  0.900
rpe
Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.
  
  
 0.895
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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