AFE_3305 protein (Acidithiobacillus ferrooxidans)

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AFE_3305

Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543. (277 aa)

Predicted Functional Partners:

thiE

0.999

thiC

0.991

thiG

0.943

AFE_0227

0.879

thiS

0.869

moeB

0.852

hemL

0.831

AFE_3302

0.794

AFE_3306

0.608

hemD

0.569

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_0227	AFE_3305	AFE_0227	AFE_3305	Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family.	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	0.879
AFE_0227	moeB	AFE_0227	AFE_0652	Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family.	Molybdopterin biosynthesis MoeB protein; Identified by similarity to SP:P12282; match to protein family HMM PF00899; match to protein family HMM PF05237.	0.713
AFE_0227	thiC	AFE_0227	AFE_0948	Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.877
AFE_0227	thiG	AFE_0227	AFE_0643	Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family.	Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.907
AFE_0227	thiS	AFE_0227	AFE_0642	Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family.	Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.	0.904
AFE_3302	AFE_3305	AFE_3302	AFE_3305	HIT family protein; Identified by match to protein family HMM PF01230.	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	0.794
AFE_3302	AFE_3306	AFE_3302	AFE_3306	HIT family protein; Identified by match to protein family HMM PF01230.	Hypothetical protein; Identified by glimmer; putative.	0.608
AFE_3302	hemD	AFE_3302	AFE_3299	HIT family protein; Identified by match to protein family HMM PF01230.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.481
AFE_3302	hemL	AFE_3302	AFE_3303	HIT family protein; Identified by match to protein family HMM PF01230.	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by similarity to SP:P48247; match to protein family HMM PF00202; match to protein family HMM TIGR00713.	0.785
AFE_3302	thiE	AFE_3302	AFE_3304	HIT family protein; Identified by match to protein family HMM PF01230.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.784
AFE_3305	AFE_0227	AFE_3305	AFE_0227	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	Mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family.	0.879
AFE_3305	AFE_3302	AFE_3305	AFE_3302	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	HIT family protein; Identified by match to protein family HMM PF01230.	0.794
AFE_3305	AFE_3306	AFE_3305	AFE_3306	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	Hypothetical protein; Identified by glimmer; putative.	0.608
AFE_3305	hemD	AFE_3305	AFE_3299	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.569
AFE_3305	hemL	AFE_3305	AFE_3303	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by similarity to SP:P48247; match to protein family HMM PF00202; match to protein family HMM TIGR00713.	0.831
AFE_3305	moeB	AFE_3305	AFE_0652	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	Molybdopterin biosynthesis MoeB protein; Identified by similarity to SP:P12282; match to protein family HMM PF00899; match to protein family HMM PF05237.	0.852
AFE_3305	thiC	AFE_3305	AFE_0948	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.991
AFE_3305	thiE	AFE_3305	AFE_3304	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.999
AFE_3305	thiG	AFE_3305	AFE_0643	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.943
AFE_3305	thiS	AFE_3305	AFE_0642	Phosphomethylpyrimidine kinase, putative; Identified by match to protein family HMM PF08543.	Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.	0.869

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