Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DET0045Redox family protein; Identified by similarity to OMNI:CT0642; match to protein family HMM TIGR01909. (148 aa)    
Predicted Functional Partners:
DET0819
Thymidylate synthase, putative; Identified by similarity to SP:P80305.
 
  
 0.877
pheT
phenylalanyl-tRNA synthetase, beta subunit; Identified by similarity to SP:P17922; match to protein family HMM PF01588; match to protein family HMM PF03483; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
   
 0.632
tyrA
Chorismate mutase/prephenate dehydratase.
     
 0.625
DET1244
NADPH-dependent FMN reductase.
 
     0.556
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
    
 
 0.549
DET1086
ATP-dependent Clp protease, proteolytic subunit ClpP, putative; Belongs to the peptidase S14 family.
    
 
 0.549
DET1251
NADPH-dependent FMN reductase.
 
     0.514
DET1622
Conserved hypothetical protein; Identified by similarity to OMNI:CT0707; match to protein family HMM PF03479.
  
     0.500
DET0044
Conserved hypothetical protein; Identified by similarity to GP:29607780.
       0.489
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.488
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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