STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET0045Redox family protein; Identified by similarity to OMNI:CT0642; match to protein family HMM TIGR01909. (148 aa)    
Predicted Functional Partners:
DET0819
Thymidylate synthase, putative; Identified by similarity to SP:P80305.
 
  
 0.920
tyrA
Chorismate mutase/prephenate dehydratase.
     
 0.597
DET1244
NADPH-dependent FMN reductase.
 
     0.555
DET1251
NADPH-dependent FMN reductase.
 
     0.513
DET1622
Conserved hypothetical protein; Identified by similarity to OMNI:CT0707; match to protein family HMM PF03479.
  
     0.500
DET0044
Conserved hypothetical protein; Identified by similarity to GP:29607780.
       0.489
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.481
DET1371
NADPH-dependent FMN reductase.
 
     0.424
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.411
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.401
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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