Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DET0069HNH endonuclease domain protein. (118 aa)    
Predicted Functional Partners:
DET0070
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.822
DET0068
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
DET0065
Virulence-related protein; Identified by similarity to GP:3482866.
 
    0.683
DET1088
Terminase, large subunit, putative.
 
  
 0.661
DET1091
Virulence-related protein; Identified by similarity to GP:3482866.
 
    0.661
DET1093
Hypothetical protein; Identified by Glimmer2; putative.
 
    0.618
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
   
    0.596
DET1087
Portal protein, HK97 family, putative; Identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537.
 
  
 0.531
DET1095
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.498
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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