Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DET0071SNF2 family helicase, putative. (513 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.856
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.833
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.825
DET0074
DNA-dependent DNA polymerase, family A; Identified by similarity to SP:P06225.
 
 
   0.819
DET1097
Conserved hypothetical protein; Identified by similarity to OMNI:EF0329.
 
     0.785
DET1101
Conserved hypothetical protein; Identified by similarity to GP:18920552.
 
     0.784
DET1102
Conserved hypothetical protein; Identified by similarity to OMNI:EF0319.
 
     0.784
DET1100
DNA-dependent DNA polymerase, family A.
  
 
   0.779
DET0330
Identified by match to protein family HMM PF00850.
    
 0.772
DET0072
Phage/plasmid DNA primase, putative; Identified by match to protein family HMM TIGR01613.
 
     0.710
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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