Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DET0103Molybdopterin oxidoreductase, iron-sulfur binding subunit, putative; Identified by similarity to SP:P32708. (312 aa)    
Predicted Functional Partners:
DET0102
Molybdopterin oxidoreductase, membrane subunit, putative.
 
 0.991
DET0101
Molybdopterin oxidoreductase; Identified by match to protein family HMM PF00384; match to protein family HMM PF04879; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.982
DET0187
Formate dehydrogenase, alpha subunit; Identified by match to protein family HMM TIGR01409; match to protein family HMM TIGR01553; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.948
DET0186
Formate dehydrogenase, membrane subunit, putative.
 
 
 0.922
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.818
DET0147
[Fe] hydrogenase, large subunit HymC, putative; Identified by similarity to GP:14250935; match to protein family HMM PF02256.
  
  
 0.815
mobA
mobA family protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
     0.765
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.695
DET1131
Pyridine nucleotide-disulfide oxidoreductase family protein.
   
 
 0.615
DET0185
Formate dehydrogenase accessory protein FdhE, putative; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
  
 0.528
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.