STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET0110[Ni/Fe] hydrogenase, group 1, large subunit, putative; Identified by similarity to SP:P21852; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (526 aa)    
Predicted Functional Partners:
DET0111
[Ni/Fe] hydrogenase, group 1, small subunit, putative; Identified by similarity to SP:P12943; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409.
 
 0.998
DET0109
Hydrogenase maturation protease; Identified by similarity to SP:P37182; match to protein family HMM TIGR00072.
 
  
 0.972
DET0614
Hydrogenase, group 3, VhuG subunit, putative; Identified by similarity to GP:1747407.
 
 
 0.871
DET0214
Iron-sulfur cluster-binding protein/coenzyme F420-reducing hydrogenase, beta subunit, putative; Identified by similarity to SP:P19499; match to protein family HMM PF04422.
  
 
 0.816
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.778
DET0186
Formate dehydrogenase, membrane subunit, putative.
 
  
 0.755
hypD
Hydrogenase expression/formation protein HypD; Identified by similarity to SP:P24192; match to protein family HMM PF01924; match to protein family HMM TIGR00075.
 
 
 0.737
hypF
[NiFe] hydrogenase maturation protein HypF; Identified by similarity to SP:O07451; match to protein family HMM TIGR00143.
 
 
 
 0.661
DET0102
Molybdopterin oxidoreductase, membrane subunit, putative.
 
  
 0.654
DET0112
[Ni/Fe] hydrogenase, iron-sulfur cluster-binding subunit, putative; Identified by similarity to SP:P33389.
  
  
 0.652
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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