| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DET0125 | trpD-1 | DET0125 | DET0126 | Alcohol dehydrogenase, zinc-containing; Identified by similarity to SP:P39400. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.728 |
| pheA | trpC | DET1547 | DET1484 | Prephenate dehydratase; Identified by similarity to SP:P07022; match to protein family HMM PF00800. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.475 |
| pheA | trpD-1 | DET1547 | DET0126 | Prephenate dehydratase; Identified by similarity to SP:P07022; match to protein family HMM PF00800. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.540 |
| pheA | trpD-2 | DET1547 | DET1483 | Prephenate dehydratase; Identified by similarity to SP:P07022; match to protein family HMM PF00800. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.449 |
| pheA | tyrA | DET1547 | DET0461 | Prephenate dehydratase; Identified by similarity to SP:P07022; match to protein family HMM PF00800. | Chorismate mutase/prephenate dehydratase. | 0.927 |
| trpA | trpB | DET1488 | DET1487 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
| trpA | trpC | DET1488 | DET1484 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
| trpA | trpD-1 | DET1488 | DET0126 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.950 |
| trpA | trpD-2 | DET1488 | DET1483 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.991 |
| trpA | trpE | DET1488 | DET1481 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.981 |
| trpA | trpF | DET1488 | DET1485 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family. | 0.999 |
| trpA | trpG | DET1488 | DET1482 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Anthranilate synthase component II; Identified by similarity to PIR:A01122; match to protein family HMM TIGR00566. | 0.992 |
| trpA | tyrA | DET1488 | DET0461 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Chorismate mutase/prephenate dehydratase. | 0.629 |
| trpB | trpA | DET1487 | DET1488 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.999 |
| trpB | trpC | DET1487 | DET1484 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
| trpB | trpD-1 | DET1487 | DET0126 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.843 |
| trpB | trpD-2 | DET1487 | DET1483 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.975 |
| trpB | trpE | DET1487 | DET1481 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.992 |
| trpB | trpF | DET1487 | DET1485 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family. | 0.999 |
| trpB | trpG | DET1487 | DET1482 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Anthranilate synthase component II; Identified by similarity to PIR:A01122; match to protein family HMM TIGR00566. | 0.994 |