STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET0138Phosphate ABC transporter, phosphate-binding protein; Identified by match to protein family HMM TIGR02136. (278 aa)    
Predicted Functional Partners:
DET0139
Phosphate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.999
DET0140
Phosphate ABC transporter, permease protein.
 
 0.999
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 0.999
phoU
Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.
 
  
 0.873
DET0136
Sensory box sensor histidine kinase; Identified by similarity to OMNI:NTL01BH3159; match to protein family HMM TIGR00229.
 
  
 0.662
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.644
arsC
Arsenate reductase; Identified by similarity to SP:P30330; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
     
 0.609
thiE
ThiE-associated domain protein/thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
   
    0.580
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
       0.570
prfB
Peptide chain release factor 2, programmed frameshift; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
 
    0.567
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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