Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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DET0187Formate dehydrogenase, alpha subunit; Identified by match to protein family HMM TIGR01409; match to protein family HMM TIGR01553; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (993 aa)    
Predicted Functional Partners:
DET0112
[Ni/Fe] hydrogenase, iron-sulfur cluster-binding subunit, putative; Identified by similarity to SP:P33389.
 0.997
DET0186
Formate dehydrogenase, membrane subunit, putative.
 
 
 0.964
DET0103
Molybdopterin oxidoreductase, iron-sulfur binding subunit, putative; Identified by similarity to SP:P32708.
 
 
 0.948
DET1133
Iron-sulfur cluster-binding protein.
 
  
 0.945
DET0147
[Fe] hydrogenase, large subunit HymC, putative; Identified by similarity to GP:14250935; match to protein family HMM PF02256.
    
 0.939
DET0185
Formate dehydrogenase accessory protein FdhE, putative; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
 
 
 0.934
DET0123
Pyridine nucleotide-disulphide oxidoreductase family protein.
 
 
 0.933
DET1173
Identified by match to protein family HMM PF02663.
   
 
  0.906
DET0730
[Fe] hydrogenase, HymC subunit, putative; Identified by similarity to GP:1032477.
 
    
 0.905
DET0865
Hydrogenase subunit HymC, putative; Identified by similarity to GP:1032477.
 
    
 0.904
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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