STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET0202Histidinol-phosphate phosphatase family protein/glycosyl transferase, group 2 family protein; Identified by match to protein family HMM TIGR01656; match to protein family HMM TIGR01662. (410 aa)    
Predicted Functional Partners:
gmhA
Phosphoheptose isomerase; Identified by similarity to SP:Q9AGY7.
 
 0.998
DET0205
D-glycero-D-manno-heptose 1-phosphate guanosyltransferase; Identified by similarity to GP:13491145.
 
 0.992
DET0206
D-glycero-D-manno-heptose 7-phosphate kinase, putative; Identified by similarity to GP:13491143.
  
 0.983
DET1208
Nucleotidyltransferase family protein; Identified by similarity to OMNI:NTL01TT0055.
 
 0.963
DET0204
NAD-dependent epimerase/dehydratase family protein.
 
  
 0.952
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475.
 
 
 
 0.937
DET0850
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01MM0209.
   
 0.933
DET0209
Membrane protein, putative.
 
  
 0.895
DET0203
Glycosyl transferase, group 2 family protein.
 
  
 0.878
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.856
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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