STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET0327Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SS00170. (199 aa)    
Predicted Functional Partners:
DET0326
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01TE2094; match to protein family HMM PF01935.
 
     0.955
DET0328
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01NS3859.
 
     0.924
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
     0.786
DET0549
Exonuclease SbcC, putative; Identified by similarity to SP:P13458.
 
     0.785
DET0524
PBS lyase HEAT-like repeat domain protein.
  
     0.755
DET0325
Identified by match to protein family HMM PF01734.
       0.603
DET0571
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.564
DET0114
ABC transporter, substrate-binding protein, putative; Identified by similarity to SP:P46904.
  
     0.486
DET0115
ABC transporter, permease protein, putative; Identified by similarity to SP:P75774; similarity to OMNI:NTL01BMA0802.
  
     0.471
DET0329
Transporter, LysE family.
       0.408
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.