Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DET0453Fumarate hydratase, alpha subunit, putative; Identified by similarity to SP:Q58690; match to protein family HMM PF05681; match to protein family HMM TIGR00722. (280 aa)    
Predicted Functional Partners:
DET0454
Fumarate hydratase, beta subunit, putative; Identified by similarity to SP:P14407; match to protein family HMM PF05683; match to protein family HMM TIGR00723.
 0.999
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.988
argH
Argininosuccinate lyase; Identified by similarity to SP:O34858; match to protein family HMM TIGR00838.
    
  0.813
DET0187
Formate dehydrogenase, alpha subunit; Identified by match to protein family HMM TIGR01409; match to protein family HMM TIGR01553; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.811
DET0112
[Ni/Fe] hydrogenase, iron-sulfur cluster-binding subunit, putative; Identified by similarity to SP:P33389.
     
  0.800
DET0641
Cyclase, putative.
     
  0.800
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.800
DET0452
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
DET0455
HIT domain protein.
       0.773
DET0447
Acyl CoA biotin-dependant carboxyltransferase; Identified by match to protein family HMM PF01039.
  
  
 0.548
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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