Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DET0522Conserved hypothetical protein; Identified by similarity to OMNI:NTL01ML1916. (137 aa)    
Predicted Functional Partners:
DET0521
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01OI0672.
       0.773
DET0600
Soluble hydrogenase, tritium exchange subunit; Identified by similarity to SP:P16421.
   
 
  0.630
DET0514
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01NS4782.
 
   
 0.557
mtnA
Translation initiation factor, putative, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
       0.554
DET0519
ABC transporter, permease protein, putative; Identified by similarity to OMNI:NTL01BMA0802.
       0.554
DET0520
Daunorubicin resistance ABC transporter, ATP-binding protein, putative; Identified by similarity to OMNI:TM1403; match to protein family HMM TIGR01188.
  
    0.554
ilvB
Acetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF02776; match to protein family HMM TIGR00118.
    
 0.519
DET1321
Acetyltransferase, GNAT family; Identified by similarity to GP:29897287.
    
 0.519
DET0825
2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.493
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
   
 
 0.493
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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