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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET0528Identified by match to protein family HMM PF02880. (430 aa)    
Predicted Functional Partners:
DET0529
Glucose-1-phosphate thymidylyltransferase; Identified by similarity to GP:1814004.
 
 0.993
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 0.986
DET0530
Glucose-1-phosphate thymidylyltransferase; Identified by similarity to SP:P08075.
  
 0.912
DET1208
Nucleotidyltransferase family protein; Identified by similarity to OMNI:NTL01TT0055.
 
  
 0.903
DET0205
D-glycero-D-manno-heptose 1-phosphate guanosyltransferase; Identified by similarity to GP:13491145.
 
  
 0.807
DET0509
SIS domain protein; Identified by similarity to GP:1208896; match to protein family HMM TIGR02128.
 
    0.763
recA
RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
     0.696
DET0525
Conserved hypothetical protein; Identified by similarity to OMNI:AF0525.
 
     0.664
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
   
 0.575
DET1141
Glycosyl transferase/polysaccharide deacetylase family protein; Identified by match to protein family HMM PF01522.
 
 
 
 0.561
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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