STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET0630Transcriptional regulator, Fur family; Belongs to the Fur family. (143 aa)    
Predicted Functional Partners:
DET0632
Cation ABC transporter, ATP-binding protein; Identified by similarity to SP:Q9XDA6.
  
  
 0.847
DET0633
Cation ABC transporter, permease protein; Identified by similarity to GP:5019735.
  
  
 0.827
DET0631
Cation ABC transporter, periplasmc-binding protein; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.821
DET0097
Iron dependent repressor, putative; Identified by match to protein family HMM PF02742.
  
  
 0.644
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.510
DET1581
Antioxidant, AhpC/TSA family; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.508
DET0953
Copper-translocating P-type ATPase; Identified by similarity to SP:P37279; match to protein family HMM PF00403; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525.
     
 0.501
DET0628
Radical SAM domain protein; Identified by match to protein family HMM TIGR00238.
       0.489
DET0629
D-ala D-ala ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
       0.489
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.425
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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