STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobD-2Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (308 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 0.984
DET0653
Conserved hypothetical protein; Identified by similarity to OMNI:MJ1613.
    
  0.976
cobU-1
Cobinamide kinase/cobinamide phosphate guanylyltransferase; Identified by similarity to SP:P46886.
 
 
 0.946
cobD-4
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
  
 
0.909
cobA-2
cob(I)alamin adenosyltransferase; Identified by similarity to GP:11513599.
    
 0.907
cobA-1
cob(I)alamin adenosyltransferase; Identified by similarity to SP:P13040.
    
 0.900
cobA-3
cob(I)alamin adenosyltransferase; Identified by similarity to GB:AAA71929.1.
    
 0.900
DET0655
Histidinol-phosphate aminotransferase, putative; Identified by similarity to SP:P17731.
   
 0.828
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
  
 0.820
DET0652
ABC-type cobalamin/Fe3+-siderophores transport system, ATP-binding protein; Identified by similarity to SP:P23878.
       0.773
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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