Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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cobS-1Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (254 aa)    
Predicted Functional Partners:
cobU-1
Cobinamide kinase/cobinamide phosphate guanylyltransferase; Identified by similarity to SP:P46886.
 
 
 0.991
DET0659
Alpha-ribazole-5-phosphate phosphatase, putative; Identified by similarity to SP:P52086.
 
 
 0.980
cobT-1
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.959
cobA-1
cob(I)alamin adenosyltransferase; Identified by similarity to SP:P13040.
  
 
 0.909
cobA-2
cob(I)alamin adenosyltransferase; Identified by similarity to GP:11513599.
  
 
 0.909
cobA-3
cob(I)alamin adenosyltransferase; Identified by similarity to GB:AAA71929.1.
  
 
 0.909
cobU-2
Cobinamide kinase/cobinamide phosphate guanylyltransferase; Identified by similarity to SP:P46886.
 
  
 0.819
cobT-2
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Identified by similarity to SP:P36562.
 
  
 0.790
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.717
DET0656
Hypothetical protein; Identified by Glimmer2; putative.
       0.482
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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