Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DET0670Iron-sulfur cluster binding protein. (640 aa)    
Predicted Functional Partners:
acsD-1
Corrinoid/iron-sulfur protein, small subunit; Identified by similarity to SP:Q07341.
 
 
   0.925
acsF-1
Carbon monoxide dehydrogenase nickel-insertion accessory protein; Identified by similarity to GP:20467243; match to protein family HMM PF00991.
 
     0.906
acsC-1
Corrinoid/iron-sulfur protein, large subunit; Identified by similarity to SP:Q07340.
 
 
 0.887
DET0666
Carbon monoxide dehydrogenase, alpha subunit; Identified by similarity to SP:P27988; match to protein family HMM TIGR00316.
 
     0.877
acsC-2
Corrinoid/iron-sulfur protein, large subunit; Identified by similarity to SP:Q07340; match to protein family HMM PF04060.
 
 
 0.792
acsD-2
Corrinoid/iron-sulfur protein, small subunit; Identified by similarity to SP:Q07341.
 
 
   0.790
folD-1
Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.775
DET0700
Carbon monoxide dehydrogenase, alpha subunit; Identified by similarity to SP:P27988; match to protein family HMM TIGR00316.
 
     0.758
DET0664
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.715
fhs-1
Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
     
 0.670
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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