Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tkt-2Transketolase; Identified by match to protein family HMM TIGR00232. (666 aa)    
Predicted Functional Partners:
tal
Transaldolase, putative; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.877
DET0677
Ribose-5-phosphate isomerase, putative; Identified by match to protein family HMM TIGR00689; match to protein family HMM TIGR01120.
     
 0.795
pheT
phenylalanyl-tRNA synthetase, beta subunit; Identified by similarity to SP:P17922; match to protein family HMM PF01588; match to protein family HMM PF03483; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.729
pgk
Phosphoglycerate kinase; Identified by similarity to SP:P40924; match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family.
  
 
 0.657
DET0679
Nitroreductase family protein; Identified by similarity to OMNI:NTL01CA1531.
  
    0.641
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.614
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.551
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.542
DET0384
Identified by similarity to SP:P50099; match to protein family HMM TIGR01304.
   
 
 0.524
tyrA
Chorismate mutase/prephenate dehydratase.
  
  
 0.511
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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