STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET0722Sodium/hydrogen exchanger family protein; Identified by similarity to SP:P26235. (427 aa)    
Predicted Functional Partners:
DET1627
Sodium/hydrogen exchanger family protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
0.750
DET0953
Copper-translocating P-type ATPase; Identified by similarity to SP:P37279; match to protein family HMM PF00403; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525.
  
  
 0.632
DET0721
Hypothetical protein; Identified by Glimmer2; putative.
       0.592
porG
Pyruvic-ferredoxin oxidoreductase, gamma subunit; Identified by similarity to SP:Q51799.
       0.482
DET0729
[Fe] hydrogenase, HymB subunit, putative; Identified by similarity to GP:14250934.
       0.453
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.442
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.442
porD
Pyruvic-ferredoxin oxidoreductase, delta subunit; Identified by similarity to SP:Q51803.
       0.430
porA
Pyruvic-ferredoxin oxidoreductase, alpha subunit; Identified by similarity to SP:Q51804.
       0.430
porB
Pyruvic-ferredoxin oxidoreductase, beta subunit; Identified by similarity to SP:Q51805.
       0.430
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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