Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DET0862Hydrogenase, group 4, EchC subunit, putative; Identified by similarity to GP:3005969. (155 aa)    
Predicted Functional Partners:
DET1571
Hydrogenase, group 4, HycE subunit, putative; Identified by similarity to SP:P77329; match to protein family HMM PF00346.
 
 0.998
DET0867
Hydrogenase, group 4, EchE subunit, putative; Identified by similarity to GP:3005971.
 
 0.997
DET0861
Hydrogenase, EchB subunit, putative; Identified by similarity to GP:3005968.
 
 
 0.985
nuoD
Proton-translocating NADH-quinone oxidoreductase, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
 
     0.956
DET0868
Hydrogenase, EchF subunit, putative; Identified by similarity to GP:3005972.
 
 
 0.931
DET0860
Hydrogenase, EchA subunit, putative; Identified by similarity to GP:3005967.
 
    0.871
DET0866
Hydrogenase subunit, putative; Identified by similarity to SP:P76440.
  
  
 0.791
DET1574
Hydrogenase, HycD subunit, putative; Identified by similarity to SP:P77858.
 
 
 0.789
DET0863
Hydrogenase subunit HymA, putative; Identified by similarity to GP:14250933.
       0.773
DET0864
Hydrogenase subunit HymB, putative; Identified by similarity to GP:14250934.
     
 0.757
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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